AP-C1

Modify Date: 2024-01-13 21:22:03

AP-C1 Structure
AP-C1 structure
Common Name AP-C1
CAS Number 2234280-26-1 Molecular Weight 385.46
Density N/A Boiling Point N/A
Molecular Formula C24H23N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AP-C1


AP-C1 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C1 only weakly inhibits cGKII-dependent anion secretion[1].

 Names

Name AP-C1

 AP-C1 Biological Activity

Description AP-C1 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C1 only weakly inhibits cGKII-dependent anion secretion[1].
Related Catalog
Target

pIC50: 6.5 (cGKII)[1]

References

[1]. Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181.  

 Chemical & Physical Properties

Molecular Formula C24H23N3O2
Molecular Weight 385.46