BTK inhibitor 10
Modify Date: 2024-06-26 22:15:44
BTK inhibitor 10 structure
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Common Name | BTK inhibitor 10 | ||
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| CAS Number | 2241732-30-7 | Molecular Weight | 441.491 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H23N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BTK inhibitor 10BTK-030 is a novel BTK inhibitor. |
| Name | BTK-030 |
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| Description | BTK-030 is a novel BTK inhibitor. |
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| Related Catalog | |
| Target |
IC50: Bruton kinase (BTK)[1] |
| In Vivo | BTK inhibitor 10 (oral gavage; 30 mg/kg; 21 days; once daily) has a significant improvement in arthritis symptoms in CIA mice. The damage of each of the 4 paws in mice is divided into 0-4 to calculate the total score of the limbs. After 21 days’ oral treatment, BTK030 reduces the arthritic score to 3.62 while the control group shows a value of 8.33[1]. Animal Model: DBA/1J mice injected with collagen as a CIA model[1] Dosage: 30 mg/kg Administration: oral gavage; 21 days; once daily Result: Decreased arthritis scores significantly when it compares to control group. |
| References |
| Molecular Formula | C25H23N5O3 |
|---|---|
| Molecular Weight | 441.491 |