MD001

Modify Date: 2024-01-06 22:19:31

MD001 Structure
MD001 structure
Common Name MD001
CAS Number 2254605-76-8 Molecular Weight 398.407
Density 1.4±0.1 g/cm3 Boiling Point 575.1±45.0 °C at 760 mmHg
Molecular Formula C25H18O5 Melting Point N/A
MSDS N/A Flash Point 199.1±22.2 °C

 Use of MD001


MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ. It binds to PPARα and PPARγ but does not bind to PPARβ/δ. It increases transcriptional activity of PPARα and PPARγ and glucose consumption. MD001 decreases levels of glucose, insulin, free fatty acids, triglycerides, LDL, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) in blood and reduces the size and number of hepatic lipid droplets in diabetic db/db mice.

 Names

Name MD001
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 575.1±45.0 °C at 760 mmHg
Molecular Formula C25H18O5
Molecular Weight 398.407
Flash Point 199.1±22.2 °C
Exact Mass 398.115417
LogP 6.14
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.704

 Synonyms

2H-1-Benzopyran-2-one, 5,7-dihydroxy-8-methyl-3-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-4-phenyl-
MD001
5,7-Dihydroxy-8-methyl-4-phenyl-3-[(2E)-3-phenyl-2-propenoyl]-2H-chromen-2-one