DBCO-(PEG2-VC-PAB-MMAE)2 structure
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Common Name | DBCO-(PEG2-VC-PAB-MMAE)2 | ||
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CAS Number | 2259318-55-1 | Molecular Weight | 2835.50 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C149H224N22O32 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of DBCO-(PEG2-VC-PAB-MMAE)2DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate[1]. |
Name | DBCO-(PEG2-VC-PAB-MMAE)2 |
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Description | DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate[1]. |
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Related Catalog | |
Target |
Auristatin |
References |
[1]. Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1. |
Molecular Formula | C149H224N22O32 |
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Molecular Weight | 2835.50 |