Ethylene diacrylate

Modify Date: 2024-01-02 18:27:19

Ethylene diacrylate Structure
Ethylene diacrylate structure
 Common Name Ethylene diacrylate
CAS Number 2274-11-5 Molecular Weight 170.163
Density 1.1±0.1 g/cm3 Boiling Point 223.9±13.0 °C at 760 mmHg
Molecular Formula C8H10O4 Melting Point 184-193℃
MSDS Chinese USA Flash Point 104.9±18.2 °C
Symbol GHS06 GHS09
GHS06, GHS09		 Signal Word Danger

 Use of Ethylene diacrylate


Ethylene glycol diacrylate (Ethylene diacrylate) is a cross-linking homobifunctional reagent. Ethylene glycol diacrylate can be polymerized to form poly(ethylene glycol) diacrylate for drug delivery[1].

 Names

Name ethylene diacrylate
Synonym More Synonyms

 Ethylene diacrylate Biological Activity

Description Ethylene glycol diacrylate (Ethylene diacrylate) is a cross-linking homobifunctional reagent. Ethylene glycol diacrylate can be polymerized to form poly(ethylene glycol) diacrylate for drug delivery[1].
Related Catalog
References

[1]. Ke Luo, et al. On shockwave propagation and attenuation in poly(ethylene glycol) diacrylate hydrogels. J Mech Behav Biomed Mater. 2021 Jun;118:104423.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 223.9±13.0 °C at 760 mmHg
Melting Point 184-193℃
Molecular Formula C8H10O4
Molecular Weight 170.163
Flash Point 104.9±18.2 °C
Exact Mass 170.057907
PSA 52.60000
LogP 1.68
Appearance of Characters Liquid | Clear colorless to light yellow
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.447
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AT0350000
CHEMICAL NAME :
Acrylic acid, ethylene ester
CAS REGISTRY NUMBER :
2274-11-5
BEILSTEIN REFERENCE NO. :
1771527
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C8-H10-O4
MOLECULAR WEIGHT :
170.18
WISWESSER LINE NOTATION :
1U1VO2OV1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - excitement Behavioral - muscle contraction or spasticity
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
350 mg/m3
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - excitement Behavioral - muscle contraction or spasticity
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
570 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
16500 nmol/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,264,1991

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H312 + H332-H315-H319-H335-H411
Precautionary Statements P261-P273-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases S26;S36/S37/S39
RIDADR UN 2810 6.1/PG 3
WGK Germany 3
RTECS AT0350000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2916190090

 Synthetic Route

ETHYLENE OXIDE structure

ETHYLENE OXIDE

CAS#:75-21-8

Acrylic acid structure

Acrylic acid

CAS#:79-10-7

~%

Ethylene diacrylate Structure

Ethylene diacrylate

CAS#:2274-11-5

2-(2-hydroxyethoxy)ethyl prop-2-enoate structure

2-(2-hydroxyeth...

CAS#:13533-05-6

Detail
Literature: EP1371629 A1, ; Page 9 ;
Ethylene glycol structure

Ethylene glycol

CAS#:107-21-1

acrolein structure

acrolein

CAS#:107-02-8

~%

Ethylene diacrylate Structure

Ethylene diacrylate

CAS#:2274-11-5

Literature: US2003/216587 A1, ; Page/Page column 3-4 ;
Ethylene glycol structure

Ethylene glycol

CAS#:107-21-1

Acrylyl chloride structure

Acrylyl chloride

CAS#:814-68-6

~50%

Ethylene diacrylate Structure

Ethylene diacrylate

CAS#:2274-11-5

Literature: Stenlake; Waigh; Urwin; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 508 - 514
ETHYLENE OXIDE structure

ETHYLENE OXIDE

CAS#:75-21-8

Acrylic acid structure

Acrylic acid

CAS#:79-10-7

~9%

Ethylene diacrylate Structure

Ethylene diacrylate

CAS#:2274-11-5

Diethylene glycol diacrylate structure

Diethylene glyc...

CAS#:4074-88-8

Literature: US2004/249189 A1, ; Page 8 ;
Ethylene glycol structure

Ethylene glycol

CAS#:107-21-1

acrylic acid methyl ester structure

acrylic acid me...

CAS#:292638-85-8

~%

Ethylene diacrylate Structure

Ethylene diacrylate

CAS#:2274-11-5

2-Hydroxyethyl acrylate structure

2-Hydroxyethyl ...

CAS#:818-61-1

Literature: Journal of Molecular Catalysis B: Enzymatic, , vol. 62, # 1 p. 80 - 89
Ethylene glycol structure

Ethylene glycol

CAS#:107-21-1

Acetylene structure

Acetylene

CAS#:74-86-2

~%

Ethylene diacrylate Structure

Ethylene diacrylate

CAS#:2274-11-5

Literature: Justus Liebigs Annalen der Chemie, , vol. 582, p. 1,13, 31
Ethylene glycol structure

Ethylene glycol

CAS#:107-21-1

Acrylic acid structure

Acrylic acid

CAS#:79-10-7

~%

Ethylene diacrylate Structure

Ethylene diacrylate

CAS#:2274-11-5

Literature: Journal of Organic Chemistry, , vol. 17, p. 1302

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Synonyms

ethyleneglycol diacrylate
1,2-dimethacryloyloxyethane
Ethylene diacrylate
Ethylene diacrylate,stabilized
1,2-ethanediyl diacrylate
ethane-1,2-diyl bis(2-methylpropanoate)
ethylene glycol diisobutyrate
ehylene glycol dimethyl acrylate
ethane-1,2-diyl diacrylate
1,2-bis(2-methyl-propanoyloxy)-ethane
ethylene glycol di(2-methylpropanoate)
ethylene glycol dimethacrylate
1,2-Ethanediyl bisacrylate
ethane-1,2-diyl bisprop-2-enoate
EINECS 218-886-4
ethylene glycol diacrylate
Aethylengylkol-diisobutyrat
MFCD00008629
ETHYLENE GLYCOL DIPROPENOATE
2-Propenoic acid, 1,2-ethanediyl ester
Ethane-1,2-diyl bisacrylate
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