FXR antagonist 1
FXR antagonist 1 structure
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Common Name | FXR antagonist 1 | ||
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| CAS Number | 2295804-68-9 | Molecular Weight | 585.87 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H59NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FXR antagonist 1FXR antagonist 1 is a selective, orally active intestinal FXR antagonist with an IC50 value of 2.1 μM. FXR antagonist 1 antagonises intestinal FXR and selectively inhibits intestinal FXR signalling by feedback activation of hepatic FXR. FXR antagonist 1 can improve liver steatosis, inflammation and fibrosis in the NASH (non-alcoholic steatohepatitis) model and can be used to study NASH. |
| Name | FXR antagonist 1 |
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| Description | FXR antagonist 1 is a selective, orally active intestinal FXR antagonist with an IC50 value of 2.1 μM. FXR antagonist 1 antagonises intestinal FXR and selectively inhibits intestinal FXR signalling by feedback activation of hepatic FXR. FXR antagonist 1 can improve liver steatosis, inflammation and fibrosis in the NASH (non-alcoholic steatohepatitis) model and can be used to study NASH. |
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| Molecular Formula | C36H59NO5 |
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| Molecular Weight | 585.87 |