Azido-PEG35-amine

Modify Date: 2024-01-10 11:17:06

Azido-PEG35-amine Structure
Azido-PEG35-amine structure
Common Name Azido-PEG35-amine
CAS Number 2301851-71-6 Molecular Weight 1627.95
Density N/A Boiling Point N/A
Molecular Formula C72H146N4O35 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG35-amine


Azido-PEG35-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG35-amine
Synonym More Synonyms

 Azido-PEG35-amine Biological Activity

Description Azido-PEG35-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C72H146N4O35
Molecular Weight 1627.95

 Synonyms

Azido-PEG35 amine