CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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DN8960000
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CHEMICAL NAME :
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Benzyl alcohol, alpha-((t-butylamino)methyl)-3,5-dihydroxy-
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CAS REGISTRY NUMBER :
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23031-25-6
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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8
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MOLECULAR FORMULA :
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C12-H19-N-O3
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MOLECULAR WEIGHT :
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225.32
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WISWESSER LINE NOTATION :
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QR CQ EYQ1MX1&1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Multiple routes
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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380 ug/kg
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TOXIC EFFECTS :
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Cardiac - other changes
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REFERENCE :
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JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 244,692,1980
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - man
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DOSE/DURATION :
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714 ug/kg
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TOXIC EFFECTS :
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Behavioral - tremor Cardiac - arrhythmias (including changes in conduction) Cardiac - change in rate
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REFERENCE :
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NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10 Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year: 300,143,1979 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Multiple routes
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DOSE :
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5660 ug/kg
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SEX/DURATION :
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female 32-34 week(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Newborn - Apgar score (human only) Reproductive - Effects on Newborn - biochemical and metabolic
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REFERENCE :
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JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year: 94,449,1979
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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6 mg/kg
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SEX/DURATION :
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female 17-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - respiratory system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
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REFERENCE :
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PEREBL Pediatric Research. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1967- Volume(issue)/page/year: 25,617,1989
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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30 mg/kg
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SEX/DURATION :
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female 17-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System
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REFERENCE :
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BRBUDU Brain Research Bulletin. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1976- Volume(issue)/page/year: 23,263,1989
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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30 mg/kg
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SEX/DURATION :
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female 17-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - endocrine system
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REFERENCE :
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RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 76,269,1992
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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62500 ng/kg
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SEX/DURATION :
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female 16-20 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Maternal Effects - other effects
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REFERENCE :
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BMMBES Biochemical Medicine and Metabolic Biology. (Academic Press, Inc., Journal Customer Service, POB 6250, Duluth, MN 55802-0250) V.35- 1986- Volume(issue)/page/year: 52,128,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4191 No. of Facilities: 58 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1405 (estimated) No. of Female Employees: 941 (estimated)
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