5,7,8-Trimethoxyflavone

Modify Date: 2024-01-09 12:37:52

5,7,8-Trimethoxyflavone Structure
5,7,8-Trimethoxyflavone structure
Common Name 5,7,8-Trimethoxyflavone
CAS Number 23050-38-6 Molecular Weight 312.32
Density 1.242±0.06 g/cm3 at 760 mmHg Boiling Point 507.4±50.0 °C at 760 mmHg
Molecular Formula C18H16O5 Melting Point 167-168 °C
MSDS N/A Flash Point N/A

 Use of 5,7,8-Trimethoxyflavone


5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].

 Names

Name 5,7,8-Trimethoxyflavone

 5,7,8-Trimethoxyflavone Biological Activity

Description 5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].
Related Catalog
In Vitro 5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether; 8, 16, 32, 64 μM; for 24 hours) decreases NO production in a dose-dependent manner in RAW 264.7 macrophages. 5,7,8-Trimethoxyflavone does not change lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability[1].
References

[1]. De-Yang Shen, et al. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int J Mol Sci. 2012 Dec 27;14(1):496-514.

 Chemical & Physical Properties

Density 1.242±0.06 g/cm3 at 760 mmHg
Boiling Point 507.4±50.0 °C at 760 mmHg
Melting Point 167-168 °C
Molecular Formula C18H16O5
Molecular Weight 312.32
Storage condition 2-8°C
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