FAK ligand-Linker Conjugate 1

Modify Date: 2024-01-15 06:11:36

FAK ligand-Linker Conjugate 1 Structure
FAK ligand-Linker Conjugate 1 structure
Common Name FAK ligand-Linker Conjugate 1
CAS Number 2307461-45-4 Molecular Weight 583.58
Density N/A Boiling Point N/A
Molecular Formula C25H28F3N5O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FAK ligand-Linker Conjugate 1


FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation[1].

 Names

Name FAK ligand-Linker Conjugate 1

 FAK ligand-Linker Conjugate 1 Biological Activity

Description FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation[1].
Related Catalog
References

[1]. Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.

 Chemical & Physical Properties

Molecular Formula C25H28F3N5O6S
Molecular Weight 583.58
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