Tetrahydropiperin
Modify Date: 2024-01-04 06:07:37
Tetrahydropiperin structure
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Common Name | Tetrahydropiperin | ||
|---|---|---|---|---|
| CAS Number | 23434-88-0 | Molecular Weight | 289.369 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 469.9±24.0 °C at 760 mmHg | |
| Molecular Formula | C17H23NO3 | Melting Point | 41ºC | |
| MSDS | N/A | Flash Point | 238.0±22.9 °C | |
Use of TetrahydropiperinTetrahydropiperine, a cyclohexyl analogue of piperine, is the first natural aryl pentanamide from Piper longum[1]. Tetrahydropiperine (compound 14) inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50=23 µM)[2]. |
| Name | 5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpentan-1-one |
|---|---|
| Synonym | More Synonyms |
| Description | Tetrahydropiperine, a cyclohexyl analogue of piperine, is the first natural aryl pentanamide from Piper longum[1]. Tetrahydropiperine (compound 14) inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50=23 µM)[2]. |
|---|---|
| Related Catalog | |
| Target |
CYP1A1:23 μM (IC50) |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 469.9±24.0 °C at 760 mmHg |
| Melting Point | 41ºC |
| Molecular Formula | C17H23NO3 |
| Molecular Weight | 289.369 |
| Flash Point | 238.0±22.9 °C |
| Exact Mass | 289.167786 |
| PSA | 38.77000 |
| LogP | 3.67 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.556 |
| Storage condition | -20℃ |
|
~96%
Tetrahydropiperin CAS#:23434-88-0 |
| Literature: Sondengam, B. Lucas; Fomum, Z. Tanee; Charles, Georges; Akam, T. Mac Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 1219 - 1222 |
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~%
Tetrahydropiperin CAS#:23434-88-0 |
| Literature: Kiuchi, Fumiyuki; Nakamura, Norio; Saito, Makiko; Komagome, Kazue; Hiramatsu, Hirokuni; Takimoto, Noriaki; Akao, Nobuaki; Kondo, Kaoru; Tsuda, Yoshisuke Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 4 p. 685 - 696 |
| Precursor 2 | |
|---|---|
| DownStream 1 | |
CAS#:110-89-4| 1-[5-(1,3-Benzodioxol-5-yl)pentanoyl]piperidine |
| Tetrahydropiperidine |
| 5-(1,3-Benzodioxol-5-yl)-1-(piperidin-1-yl)pentan-1-one |
| Tetrahydropiperin |
| 1-Pentanone, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)- |
| 5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-1-pentanone |
| Piperidine, 1-[5-(1,3-benzodioxol-5-yl)-1-oxopentyl]- |
| Cosmoperine |
| Tetrahydropiperine |