![]() MEN 11270 structure
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Common Name | MEN 11270 | ||
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CAS Number | 235082-52-7 | Molecular Weight | 1299.55 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C60H90N20O11S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of MEN 11270MEN 11270, a cyclic decapeptide, is a B2 kinin receptor antagonist. MEN 11270 bound with high-affinity to the B2 kinin receptor constitutively expressed by WI38 human fibroblasts, inhibiting 3H-bradykinin (BK) with a pKi value of 10.3[1]. |
Name | D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-N-[(8S,13S,15aS,22aR)-13-(3-carbamimidamidopropyl)-7,12,15,22-tetraoxo-5,8,9,10,11,12,13,14,15,15a,16,16a,17,18,19,20,20a,22,22a,23-icosahydro-7H-indolo[1',2':4,5][1,4,7,10]tetraazacyclotetradecino[1,2-b]isoquinolin-8-yl]-3-(2-thienyl)-D-alaninamide |
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Synonym | More Synonyms |
Description | MEN 11270, a cyclic decapeptide, is a B2 kinin receptor antagonist. MEN 11270 bound with high-affinity to the B2 kinin receptor constitutively expressed by WI38 human fibroblasts, inhibiting 3H-bradykinin (BK) with a pKi value of 10.3[1]. |
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Related Catalog | |
References |
Density | 1.6±0.1 g/cm3 |
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Molecular Formula | C60H90N20O11S |
Molecular Weight | 1299.55 |
Exact Mass | 1298.681885 |
LogP | -5.38 |
Index of Refraction | 1.755 |
D-Alaninamide, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-N-[(8S,13S,15aS,22aR)-13-[3-[(aminoiminomethyl)amino]propyl]-5,8,9,10,11,12,13,14,15,15a,16,16a,17,18,19,20,20a,22,22a,23-eicosahydro-7,12,15,22-tetraoxo-7H-indolo[1',2':4,5][1,4,7,10]tetraazacyclotetradecino[1,2-b]isoquinolin-8-yl]-3-(2-thienyl)- |
D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-N-[(8S,13S,15aS,22aR)-13-(3-carbamimidamidopropyl)-7,12,15,22-tetraoxo-5,8,9,10,11,12,13,14,15,15a,16,16a,17,18,19,20,20a,22,22a,23-icosahydro-7H-indolo[1',2':4,5][1,4,7,10]tetraazacyclotetradecino[1,2-b]isoquinolin-8-yl]-3-(2-thienyl)-D-alaninamide |