MEN 11270

Modify Date: 2024-02-26 20:10:45

MEN 11270 structure	Common Name	MEN 11270
	CAS Number	235082-52-7	Molecular Weight	1299.55
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₆₀H₉₀N₂₀O₁₁S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MEN 11270

MEN 11270, a cyclic decapeptide, is a B2 kinin receptor antagonist. MEN 11270 bound with high-affinity to the B2 kinin receptor constitutively expressed by WI38 human fibroblasts, inhibiting 3H-bradykinin (BK) with a pKi value of 10.3[1].

Name	D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-N-[(8S,13S,15aS,22aR)-13-(3-carbamimidamidopropyl)-7,12,15,22-tetraoxo-5,8,9,10,11,12,13,14,15,15a,16,16a,17,18,19,20,20a,22,22a,23-icosahydro-7H-indolo[1',2':4,5][1,4,7,10]tetraazacyclotetradecino[1,2-b]isoquinolin-8-yl]-3-(2-thienyl)-D-alaninamide
Synonym	More Synonyms

Description	MEN 11270, a cyclic decapeptide, is a B2 kinin receptor antagonist. MEN 11270 bound with high-affinity to the B2 kinin receptor constitutively expressed by WI38 human fibroblasts, inhibiting 3H-bradykinin (BK) with a pKi value of 10.3[1].
Related Catalog	Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Bradykinin Receptor
References	[1]. Meini S, et, al. MEN 11270, A novel selective constrained peptide antagonist with high affinity at the human B2 kinin receptor. J Pharmacol Exp Ther. 1999 Jun;289(3):1250-6.

Density	1.6±0.1 g/cm3
Molecular Formula	C₆₀H₉₀N₂₀O₁₁S
Molecular Weight	1299.55
Exact Mass	1298.681885
LogP	-5.38
Index of Refraction	1.755

D-Alaninamide, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-N-[(8S,13S,15aS,22aR)-13-[3-[(aminoiminomethyl)amino]propyl]-5,8,9,10,11,12,13,14,15,15a,16,16a,17,18,19,20,20a,22,22a,23-eicosahydro-7,12,15,22-tetraoxo-7H-indolo[1',2':4,5][1,4,7,10]tetraazacyclotetradecino[1,2-b]isoquinolin-8-yl]-3-(2-thienyl)-

D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-N-[(8S,13S,15aS,22aR)-13-(3-carbamimidamidopropyl)-7,12,15,22-tetraoxo-5,8,9,10,11,12,13,14,15,15a,16,16a,17,18,19,20,20a,22,22a,23-icosahydro-7H-indolo[1',2':4,5][1,4,7,10]tetraazacyclotetradecino[1,2-b]isoquinolin-8-yl]-3-(2-thienyl)-D-alaninamide

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MEN 11270
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MEN 11270
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

MEN 11270 suppliers

MEN 11270 price

MEN 11270

Use of MEN 11270

Names

MEN 11270 Biological Activity

Chemical & Physical Properties

Synonyms