TCO-PEG8-TCO

Modify Date: 2024-01-06 20:59:35

TCO-PEG8-TCO Structure
TCO-PEG8-TCO structure
Common Name TCO-PEG8-TCO
CAS Number 2353409-67-1 Molecular Weight 716.90
Density N/A Boiling Point N/A
Molecular Formula C36H64N2O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TCO-PEG8-TCO


TCO-PEG8-TCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name TCO-PEG8-TCO

 TCO-PEG8-TCO Biological Activity

Description TCO-PEG8-TCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

 Chemical & Physical Properties

Molecular Formula C36H64N2O12
Molecular Weight 716.90