Bis-PEG1-C-PEG1-CH2COOH

Modify Date: 2024-02-04 19:35:00

Bis-PEG1-C-PEG1-CH2COOH Structure
Bis-PEG1-C-PEG1-CH2COOH structure
Common Name Bis-PEG1-C-PEG1-CH2COOH
CAS Number 2358775-67-2 Molecular Weight 350.40
Density N/A Boiling Point N/A
Molecular Formula C16H30O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-PEG1-C-PEG1-CH2COOH


PROTAC Linker 26 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 26 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name PROTAC Linker 26

 Bis-PEG1-C-PEG1-CH2COOH Biological Activity

Description PROTAC Linker 26 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 26 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C16H30O8
Molecular Weight 350.40
Storage condition -20°C