DBCO-PEG5-DBCO

Modify Date: 2024-01-10 12:13:16

DBCO-PEG5-DBCO Structure
DBCO-PEG5-DBCO structure
Common Name DBCO-PEG5-DBCO
CAS Number 2363130-04-3 Molecular Weight 854.99
Density N/A Boiling Point N/A
Molecular Formula C50H54N4O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG5-DBCO


DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG5-DBCO

 DBCO-PEG5-DBCO Biological Activity

Description DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C50H54N4O9
Molecular Weight 854.99