MMP-8 INHIBITOR I

Modify Date: 2024-01-08 15:52:33

MMP-8 INHIBITOR I Structure
MMP-8 INHIBITOR I structure
Common Name MMP-8 INHIBITOR I
CAS Number 236403-25-1 Molecular Weight 362.40
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C17H18N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MMP-8 INHIBITOR I


MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability[1].

 Names

Name (3R)-N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
Synonym More Synonyms

 MMP-8 INHIBITOR I Biological Activity

Description MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability[1].
Related Catalog
Target

MMP-8

References

[1]. Matter H, et al. Tetrahydroisoquinoline-3-carboxylate based matrix-metalloproteinase inhibitors: design, synthesis and structure-activity relationship. Bioorg Med Chem. 2002 Nov;10(11):3529-44.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C17H18N2O5S
Molecular Weight 362.40
Exact Mass 362.093628
LogP 2.05
Index of Refraction 1.629

 Synonyms

(3R)-N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-