PCSK9 modulator-2

Modify Date: 2024-01-12 12:12:07

PCSK9 modulator-2 Structure
PCSK9 modulator-2 structure
Common Name PCSK9 modulator-2
CAS Number 2365416-53-9 Molecular Weight 282.29
Density N/A Boiling Point N/A
Molecular Formula C17H12F2N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PCSK9 modulator-2


PCSK9 modulator-2 (Compound 1) is a potent modulator of PCSK9 with an EC50 value of 202 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-2 has the potential for the research of hyperlipidemia[1].

 Names

Name PCSK9 modulator-2

 PCSK9 modulator-2 Biological Activity

Description PCSK9 modulator-2 (Compound 1) is a potent modulator of PCSK9 with an EC50 value of 202 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-2 has the potential for the research of hyperlipidemia[1].
Related Catalog
References

[1]. Xie H, et al. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. Eur J Med Chem. 2020 Nov 15;206:112678.

 Chemical & Physical Properties

Molecular Formula C17H12F2N2
Molecular Weight 282.29