Olaquindox

Modify Date: 2024-01-02 18:00:00

Olaquindox Structure
Olaquindox structure
 Common Name Olaquindox
CAS Number 23696-28-8 Molecular Weight 263.249
Density 1.4±0.1 g/cm3 Boiling Point 343.3ºC
Molecular Formula C12H13N3O4 Melting Point 209°C (dec.)
MSDS Chinese USA Flash Point >204.4ºC
Symbol GHS07 GHS08
GHS07, GHS08		 Signal Word Danger

 Use of Olaquindox


Olaquindox, a quinoxalin derivative, is an orally active antibiotic veterinary drug. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets[1].

 Names

Name N-(2-hydroxyethyl)-3-methyl-4-oxido-1-oxoquinoxalin-1-ium-2-carboxamide
Synonym More Synonyms

 Olaquindox Biological Activity

Description Olaquindox, a quinoxalin derivative, is an orally active antibiotic veterinary drug. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets[1].
Related Catalog
In Vivo Olaquindox (100 mg/kg in the basal diet) improves average daily gain and feed conversion ratio (FCR)[1].
References

[1]. Ding MX, et al. Olaquindox and cyadox stimulate growth and decrease intestinal mucosal immunityof piglets orally inoculated with Escherichia coli. J Anim Physiol Anim Nutr (Berl). 2006 Jun;90(5-6):238-43.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 343.3ºC
Melting Point 209°C (dec.)
Molecular Formula C12H13N3O4
Molecular Weight 263.249
Flash Point >204.4ºC
Exact Mass 263.090607
PSA 100.25000
LogP -2.20
Index of Refraction 1.651
Storage condition 0-6°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VD1582000
CHEMICAL NAME :
2-Quinoxalinecarboxamide, N-(2-hydroxyethyl)-3-methyl-, 1,4-dioxide
CAS REGISTRY NUMBER :
23696-28-8
LAST UPDATED :
199612
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C12-H13-N3-O4
MOLECULAR WEIGHT :
263.28
WISWESSER LINE NOTATION :
T66 BN ENJ BO CVM2Q D1 EO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1717 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4550 mg/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
20 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 139,199,1984

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H302-H334
Precautionary Statements P261-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R43
Safety Phrases S36/37
RIDADR NONH for all modes of transport
RTECS VD1582000
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles26

More Articles
First detection of oqxAB in Salmonella spp. isolated from food.

Antimicrob. Agents Chemother. 57(1) , 658-60, (2013)

Food-borne salmonellosis is an important public health problem worldwide and the second leading cause of food-borne illnesses in Hong Kong. In this study, the prevalence and antimicrobial resistance o...

Reduction of carbadox mediated by reaction of Mn(III) with oxalic acid.

Environ. Sci. Technol. 47(3) , 1357-64, (2013)

Manganese(III) geocomponents are commonly found in the soil environment, yet their roles in many biogeochemical processes remain unknown. In this study, we demonstrated that Mn(III) generated from the...

Residue depletion and tissue-plasma correlation of methyl-3-quinoxaline-2-carboxylic acid after dietary administration of olaquindox in pigs.

J. Agric. Food Chem. 58(2) , 937-42, (2010)

A residue depletion study was performed to investigate the tissue kinetics and tissue-plasma correlation of methyl-3-quinoxaline-2-carboxylic acid (MQCA), the marker residue of olaquindox (OLA), in pi...

 Synonyms

Bisergon
2-((2-Hydroxyethyl)carbamoyl)-3-methylquinoxaline 1,4-dioxide
MFCD00210341
3-methyl-1,4-dioxy-quinoxaline-2-carboxylic acid 2-hydroxy-ethylamide
EINECS 245-832-7
Olaguindox
Bayernox
Olachindox
Bayonox
Olaquindox
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Chemsrc provides Olaquindox(CAS#:23696-28-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Olaquindox are included as well.>> amp version: Olaquindox

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