8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one,10-methoxy-

Modify Date: 2024-02-26 13:44:28

8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one,10-methoxy- Structure
8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one,10-methoxy- structure
Common Name 8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one,10-methoxy-
CAS Number 23740-25-2 Molecular Weight 305.28
Density 1.472g/cm3 Boiling Point 572.5ºC at 760mmHg
Molecular Formula C18H11NO4 Melting Point N/A
MSDS N/A Flash Point 300.1ºC

 Use of 8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one,10-methoxy-


Lanuginosine (Compound 12) is an AChE inhibitor (IC50: 10.9 μM). Lanuginosine inhibits Aβ aggregation. Lanuginosine can be used for research of Alzheimer’s disease[1].

 Names

Name lanuginosine
Synonym More Synonyms

  Biological Activity

Description Lanuginosine (Compound 12) is an AChE inhibitor (IC50: 10.9 μM). Lanuginosine inhibits Aβ aggregation. Lanuginosine can be used for research of Alzheimer’s disease[1].
Related Catalog
Target

10.9 μM (AChE)[1]

References

[1]. Jiang K, et al. Bioactive Isoquinoline Alkaloids with Diverse Skeletons from Fissistigma polyanthum. J Nat Prod. 2023 Aug 24.  

 Chemical & Physical Properties

Density 1.472g/cm3
Boiling Point 572.5ºC at 760mmHg
Molecular Formula C18H11NO4
Molecular Weight 305.28
Flash Point 300.1ºC
Exact Mass 305.06900
PSA 57.65000
LogP 3.18350
Vapour Pressure 4.07E-13mmHg at 25°C
Index of Refraction 1.729

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RB6035500
CHEMICAL NAME :
Noraporphin-7-one, 4,5,6,6a-tetradehydro-9-methoxy-1,2-(methylenedioxy)-
CAS REGISTRY NUMBER :
23740-25-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C18-H11-N-O4
MOLECULAR WEIGHT :
305.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
3 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,267,1990

 Safety Information

HS Code 2934999090

 Synthetic Route

~%

8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one,10-methoxy- Structure

8H-Benzo[g]-1,3...

CAS#:23740-25-2

Literature: Govindachari,T.R. et al. Indian Journal of Chemistry, 1970 , vol. 8, p. 475 - 477

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

10-Methoxy-8H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one
Oxoxylopine
10-methoxy-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-8-one
9-METHOXY-1,2-METHYLENEDIOXY-7-OXAPORPHINE