Boc-C1-PEG3-C4-OH

Modify Date: 2024-01-09 14:42:09

Boc-C1-PEG3-C4-OH Structure
Boc-C1-PEG3-C4-OH structure
Common Name Boc-C1-PEG3-C4-OH
CAS Number 2376724-97-7 Molecular Weight 320.42
Density N/A Boiling Point N/A
Molecular Formula C16H32O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-C1-PEG3-C4-OH


Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the alkyl chain composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name Boc-C1-PEG3-C4-OH

 Boc-C1-PEG3-C4-OH Biological Activity

Description Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the alkyl chain composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

 Chemical & Physical Properties

Molecular Formula C16H32O6
Molecular Weight 320.42

 Safety Information

Hazard Codes Xi