Antitumor agent-59

Modify Date: 2024-01-15 12:54:26

Antitumor agent-59 structure	Common Name	Antitumor agent-59
	CAS Number	2409952-04-9	Molecular Weight	770.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₃H₃₆F₂N₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antitumor agent-59

Antitumor agent-59 (Compound 13b) is a potent antitumor agent. Antitumor agent-59 effectively inhibits the proliferation and migration of HCT116 cells. Antitumor agent-59 induces HCT116 cell apoptosis and arrests the cell cycle at the G2/M phase[1].

Name	Antitumor agent-59

Description	Antitumor agent-59 (Compound 13b) is a potent antitumor agent. Antitumor agent-59 effectively inhibits the proliferation and migration of HCT116 cells. Antitumor agent-59 induces HCT116 cell apoptosis and arrests the cell cycle at the G2/M phase[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Antitumor agent-59 (Compound 13b) (72 h) shows antitumor activities with IC50 values of 0.032 ± 0.0071, 0.20 ± 0.020, 0.73 ± 0.12 and 0.58 ± 0.15 μM against HCT116, MCF-7, A549 and HUVEC cells, respectively[1].
References	[1]. Liang H, et al. Discovery of novel bis-evodiamine derivatives with potent antitumor activity. Bioorg Med Chem. 2022 Jul 1;65:116793.

Molecular Formula	C₄₃H₃₆F₂N₆O₆
Molecular Weight	770.78

Antitumor agent-59

Use of Antitumor agent-59

Names

Antitumor agent-59 Biological Activity

Chemical & Physical Properties