NBD-14270
Modify Date: 2024-01-10 19:34:54
NBD-14270 structure
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Common Name | NBD-14270 | ||
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| CAS Number | 2411819-82-2 | Molecular Weight | 425.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H18F3N5O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NBD-14270NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 μM)[1][2]. |
| Name | NBD-14270 |
|---|
| Description | NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 μM)[1][2]. |
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| Related Catalog | |
| Target |
HIV-1 |
| In Vitro | NBD-14270 has anti-HIV-1 activity (IC50=0.16 μM ) and Cytotoxicity (CC50=109.3 μM) in single-cycle (TZM-bl Cells) assay[1]. NBD-14270 does not induce toxicity in the U87-CD4-CXCR4 cell line at the doses used for this assay[1]. |
| References |
| Molecular Formula | C18H18F3N5O2S |
|---|---|
| Molecular Weight | 425.43 |