EV-A71-IN-1

Modify Date: 2024-04-03 15:20:53

EV-A71-IN-1 Structure
EV-A71-IN-1 structure
Common Name EV-A71-IN-1
CAS Number 2413648-96-9 Molecular Weight 369.44
Density N/A Boiling Point N/A
Molecular Formula C21H15N5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EV-A71-IN-1


EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM)[1].

 Names

Name EV-A71-IN-1

 EV-A71-IN-1 Biological Activity

Description EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM)[1].
Related Catalog
In Vitro EV-A71-IN-1 (compound 12s) shows activity not only against different EV-A71 strains (BrCr, GZ-CII, EV71/HeN09 and EV71/G082) but also against other representative enteroviruses (CV-A16, EV-D68, Echov-6, CV-B2 and CV-B6)[1].
References

[1]. Xu Z, et al. Discovery of aminothiazole derivatives as novel human enterovirus A71 capsid protein inhibitors. Bioorg Chem. 2022;122:105683.

 Chemical & Physical Properties

Molecular Formula C21H15N5S
Molecular Weight 369.44
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: EV-A71-IN-1
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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