EMI56

Modify Date: 2024-01-02 10:37:04

EMI56 Structure
EMI56 structure
Common Name EMI56
CAS Number 2414374-41-5 Molecular Weight 348.40
Density N/A Boiling Point N/A
Molecular Formula C21H20N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EMI56


EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants[1].

 Names

Name EMI56

 EMI56 Biological Activity

Description EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants[1].
Related Catalog
Target

EGFRL858R/T790M/C797S

EGFRdel19 T790M C797S

In Vitro EMI56 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI56 can be used in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC)[1].
References

[1]. Punit Saraon , et al. A Drug Discovery Platform to Identify Compounds That Inhibit EGFR Triple Mutants.Nat Chem Biol. 2020 May;16(5):577-586.

 Chemical & Physical Properties

Molecular Formula C21H20N2O3
Molecular Weight 348.40