CDK7-IN-3

Modify Date: 2024-04-06 11:43:20

CDK7-IN-3 Structure
CDK7-IN-3 structure
Common Name CDK7-IN-3
CAS Number 2417302-07-7 Molecular Weight 490.46
Density N/A Boiling Point N/A
Molecular Formula C23H26F3N6OP Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK7-IN-3


CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity.

 Names

Name CDK7-IN-3

 CDK7-IN-3 Biological Activity

Description CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity.

 Chemical & Physical Properties

Molecular Formula C23H26F3N6OP
Molecular Weight 490.46