Name | CDK7-IN-3 |
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Description | CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity. |
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Molecular Formula | C23H26F3N6OP |
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Molecular Weight | 490.46 |