Sevasemten

Modify Date: 2024-01-29 14:52:05

Sevasemten Structure
Sevasemten structure
Common Name Sevasemten
CAS Number 2417395-15-2 Molecular Weight 381.28
Density N/A Boiling Point N/A
Molecular Formula C16H11F4N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sevasemten


Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].

 Names

Name Sevasemten

 Sevasemten Biological Activity

Description Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].
Related Catalog
References

[1]. Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18.

[2]. WHO Drug Information-World Health Organization (WHO).

 Chemical & Physical Properties

Molecular Formula C16H11F4N5O2
Molecular Weight 381.28