D-Luciferin 6′-methyl ether

Modify Date: 2024-01-02 22:11:03

D-Luciferin 6′-methyl ether Structure
D-Luciferin 6′-methyl ether structure
Common Name D-Luciferin 6′-methyl ether
CAS Number 24404-90-8 Molecular Weight 294.34900
Density N/A Boiling Point N/A
Molecular Formula C12H10N2O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of D-Luciferin 6′-methyl ether


D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site[1].

 Names

Name (S)-2-(6-methoxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid
Synonym More Synonyms

 D-Luciferin 6′-methyl ether Biological Activity

Description D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site[1].
Related Catalog
References

[1]. Giuseppe Meroni, et al. D-Luciferin, derivatives and analogues: synthesis and in vitro/in vivo luciferase-catalyzed bioluminescent activity. Volume 2009, Issue 1, Reviews and Accounts, pp. 265-288

 Chemical & Physical Properties

Molecular Formula C12H10N2O3S2
Molecular Weight 294.34900
Exact Mass 294.01300
PSA 125.32000
LogP 1.68710

 Synonyms

LucME
D-methoxyluc
lucifern 6'-methyl ether
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