Menin-MLL inhibitor 20

Modify Date: 2024-01-09 18:12:54

Menin-MLL inhibitor 20 Structure
Menin-MLL inhibitor 20 structure
Common Name Menin-MLL inhibitor 20
CAS Number 2448173-47-3 Molecular Weight 612.72
Density N/A Boiling Point N/A
Molecular Formula C33H40N8O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Menin-MLL inhibitor 20


Menin-MLL inhibitor 20 is an irreversible menin-MLL interaction inhibitor with antitumor activities (WO2020142557A1, compound 6)[1].

 Names

Name Menin-MLL inhibitor 20

 Menin-MLL inhibitor 20 Biological Activity

Description Menin-MLL inhibitor 20 is an irreversible menin-MLL interaction inhibitor with antitumor activities (WO2020142557A1, compound 6)[1].
Related Catalog
In Vitro The Histone-lysine N-methyltransferase 2 (KMT2) family of proteins, which currently consists of at least 5 members, methylate ly sine 4 on the histone H3 tails at important regulatory regions in the genome and thereby impart crucial functions through the modulation of chromatin structures and DNA accessibility. These enzymes are known to play an important role in the regulation of gene expression during early development and hematopoiesis. The human KMT2 family was initially named the mixed-lineage leukaemia (MLL) family, owing to the role of the first-found member in this disease[1].
References

[1]. Thomas Butler, et al. Irreversible inhibitors of menin-mll interaction. WO2020142557A1.

 Chemical & Physical Properties

Molecular Formula C33H40N8O4
Molecular Weight 612.72
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