Phosphatidylinositol 4,5-bisphosphate

Modify Date: 2024-01-02 17:11:10

Phosphatidylinositol 4,5-bisphosphate Structure
Phosphatidylinositol 4,5-bisphosphate structure
Common Name Phosphatidylinositol 4,5-bisphosphate
CAS Number 245126-95-8 Molecular Weight 1047.088
Density 1.3±0.1 g/cm3 Boiling Point 1034.8±75.0 °C at 760 mmHg
Molecular Formula C47H85O19P3 Melting Point N/A
MSDS N/A Flash Point 579.6±37.1 °C

 Use of Phosphatidylinositol 4,5-bisphosphate


Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger[1][2][3].

 Names

Name (2R)-1-[(Hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl)oxy]-3-(stearoyloxy)-2-propanyl (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoate
Synonym More Synonyms

 Phosphatidylinositol 4,5-bisphosphate Biological Activity

Description Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger[1][2][3].
Related Catalog
References

[1]. Katan M, et, al. Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane. Essays Biochem. 2020 Sep 23;64(3):513-531.

[2]. Arreola J, et, al. Wasted TMEM16A channels are rescued by phosphatidylinositol 4,5-bisphosphate Cell Calcium. 2019 Dec;84:102103.

[3]. Kato M, et, al. Arabidopsis PCaP2 modulates the phosphatidylinositol 4,5-bisphosphate signal on the plasma membrane and attenuates root hair elongation. Plant J. 2019 Aug;99(4):610-625.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1034.8±75.0 °C at 760 mmHg
Molecular Formula C47H85O19P3
Molecular Weight 1047.088
Flash Point 579.6±37.1 °C
Exact Mass 1046.489746
LogP 13.22
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.538

 Synonyms

(2R)-1-[(Hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl)oxy]-3-(stearoyloxy)-2-propanyl (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoate
5,8,11,14-Eicosatetraenoic acid, (1R)-2-[[hydroxy[[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy]phosphinyl]oxy]-1-[[(1-oxooctadecyl)oxy]methyl]ethyl ester, (5Z,8Z,11Z,14Z)-
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