O-benzyl-L-histidine bis(toluene-p-sulphonate)

Modify Date: 2024-01-09 16:06:02

O-benzyl-L-histidine bis(toluene-p-sulphonate) Structure
O-benzyl-L-histidine bis(toluene-p-sulphonate) structure
Common Name O-benzyl-L-histidine bis(toluene-p-sulphonate)
CAS Number 24593-59-7 Molecular Weight 589.68000
Density N/A Boiling Point 856.1ºC at 760mmHg
Molecular Formula C27H31N3O8S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of O-benzyl-L-histidine bis(toluene-p-sulphonate)


L-Histidine benzyl ester bistosylate could play a role in the activation of HutP (an RNA-binding protein)[1].

 Names

Name benzyl (2S)-2-amino-3-(1H-imidazol-5-yl)propanoate,4-methylbenzenesulfonic acid
Synonym More Synonyms

  Biological Activity

Description L-Histidine benzyl ester bistosylate could play a role in the activation of HutP (an RNA-binding protein)[1].
Related Catalog
References

[1]. Thirumananseri Kumarevel, et al. Allosteric activation of HutP protein, that regulates transcription of hut operon in Bacillus subtilis, mediated by various analogs of histidine. Nucleic Acids Res Suppl. 2003;(3):199-200.

 Chemical & Physical Properties

Boiling Point 856.1ºC at 760mmHg
Molecular Formula C27H31N3O8S2
Molecular Weight 589.68000
Exact Mass 589.15500
PSA 206.50000
LogP 6.36820
Vapour Pressure 3.24E-31mmHg at 25°C
Storage condition −20°C

 Synthetic Route

~91%

O-benzyl-L-histidine bis(toluene-p-sulphonate) Structure

O-benzyl-L-hist...

CAS#:24593-59-7

Literature: Jones, J.H.; Wood, M.E. Synthetic Communications, 1986 , vol. 16, # l2 p. 1515 - 1516

~80%

O-benzyl-L-histidine bis(toluene-p-sulphonate) Structure

O-benzyl-L-hist...

CAS#:24593-59-7

Literature: Thaqi, Ali; Scott, Janet L.; Gilbert, Jayne; Sakoff, Jennette A.; McCluskey, Adam European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1717 - 1723

~%

O-benzyl-L-histidine bis(toluene-p-sulphonate) Structure

O-benzyl-L-hist...

CAS#:24593-59-7

Literature: Akabori et al. Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 784

 Synonyms

histidine benzyl ester di-p-toluenesulfonic acid salt
histidine benzyl ester di-p-toluenesulfonate salt
EINECS 246-334-2
L-histidine benzyl ester,bis-(toluene-4-sulfonate)
L-histidine benzyl ester di-para-toluene sulfonate
(S)-Benzyl 2-amino-3-(1H-imidazol-4-yl)propanoate bis(4-methylbenzenesulfonate)
O-benzyl-L-histidine bis(toluene-p-sulphonate)
L-Histidin-benzylester,Bis-(toluol-4-sulfonat)
L-histidine benzyl ester di-p-toluenesulphonate
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