NR-160
Modify Date: 2024-01-18 15:11:00
NR-160 structure
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Common Name | NR-160 | ||
|---|---|---|---|---|
| CAS Number | 2484895-50-1 | Molecular Weight | 510.477 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H21F3N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NR-160NR-160 (NR160) is a novel potent, selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 30 nM, shows SI (75-1847 )over all HDAC class I isoforms.NR-160 induced α-tubulin acetylation (ac-α-tubulin) in treated acute myeloid leukemic (AML) cell line HL60, but not histone H3 (ac-H3) (a marker for the inhibition of class I HDACs).NR-160 enhances the cytotoxicity induction of bortezomib, epirubicin and daunorubicin on a panel of seven leukemia cell lines |
| Name | NR-160 |
|---|
| Description | NR-160 (NR160) is a novel potent, selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 30 nM, shows SI (75-1847 )over all HDAC class I isoforms.NR-160 induced α-tubulin acetylation (ac-α-tubulin) in treated acute myeloid leukemic (AML) cell line HL60, but not histone H3 (ac-H3) (a marker for the inhibition of class I HDACs).NR-160 enhances the cytotoxicity induction of bortezomib, epirubicin and daunorubicin on a panel of seven leukemia cell lines |
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| References | 1. Nina Reßing, et al. J Med Chem. 2020 Sep 24;63(18):10339-10351. |
| Molecular Formula | C25H21F3N6O3 |
|---|---|
| Molecular Weight | 510.477 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: NR-160
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Tom
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: NR-160
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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