ATX inhibitor 11

Modify Date: 2024-04-05 22:40:26

ATX inhibitor 11 structure	Common Name	ATX inhibitor 11
	CAS Number	2485779-27-7	Molecular Weight	585.65
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₃₅N₅O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ATX inhibitor 11

ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research[1].

Name	ATX inhibitor 11

Description	ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Others
Target	Autotaxin:2.7 ± 1 nM (IC50)
References	[1]. Lei H, et al. Novel imidazo[1,2-a]pyridine derivatives as potent ATX allosteric inhibitors: Design, synthesis and promising in vivo anti-fibrotic efficacy in mice lung model. Bioorg Chem. 2022 Mar;120:105590.

Molecular Formula	C₃₂H₃₅N₅O₆
Molecular Weight	585.65

ATX inhibitor 11

Use of ATX inhibitor 11

Names

ATX inhibitor 11 Biological Activity

Chemical & Physical Properties