Thalidomide-4-NH-PEG1-NH2 TFA

Modify Date: 2024-04-05 20:54:31

Thalidomide-4-NH-PEG1-NH2 TFA Structure
Thalidomide-4-NH-PEG1-NH2 TFA structure
Common Name Thalidomide-4-NH-PEG1-NH2 TFA
CAS Number 2490499-21-1 Molecular Weight 474.39
Density N/A Boiling Point N/A
Molecular Formula C19H21F3N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-4-NH-PEG1-NH2 TFA


Thalidomide-4-NH-PEG1-NH2 TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-NH2 TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

 Names

Name 1H-Isoindole-1,3(2H)-dione, 4-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-, 2,2,2-trifluoroacetate (1:1)
Synonym More Synonyms

 Thalidomide-4-NH-PEG1-NH2 TFA Biological Activity

Description Thalidomide-4-NH-PEG1-NH2 TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-NH2 TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
Related Catalog

 Chemical & Physical Properties

Molecular Formula C19H21F3N4O7
Molecular Weight 474.39

 Synonyms

1h-isoindole-1,3(2h)-dione, 4-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-, 2,2,2-tr