Thalidomide-4-NH-PEG1-NH2 TFA structure
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Common Name | Thalidomide-4-NH-PEG1-NH2 TFA | ||
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CAS Number | 2490499-21-1 | Molecular Weight | 474.39 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C19H21F3N4O7 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Thalidomide-4-NH-PEG1-NH2 TFAThalidomide-4-NH-PEG1-NH2 TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-NH2 TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules. |
Name | 1H-Isoindole-1,3(2H)-dione, 4-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-, 2,2,2-trifluoroacetate (1:1) |
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Synonym | More Synonyms |
Description | Thalidomide-4-NH-PEG1-NH2 TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-NH2 TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules. |
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Related Catalog |
Molecular Formula | C19H21F3N4O7 |
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Molecular Weight | 474.39 |
1h-isoindole-1,3(2h)-dione, 4-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-, 2,2,2-tr |