Antiparasitic agent-5

Modify Date: 2024-04-06 20:08:08

Antiparasitic agent-5 Structure
Antiparasitic agent-5 structure
Common Name Antiparasitic agent-5
CAS Number 2494276-55-8 Molecular Weight 381.81
Density N/A Boiling Point N/A
Molecular Formula C20H16ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiparasitic agent-5


Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM)[1].

 Names

Name Antiparasitic agent-5

 Antiparasitic agent-5 Biological Activity

Description Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM)[1].
Related Catalog
Target

IC50: 2.50 μM (L. infantum)[1]

References

[1]. Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.

 Chemical & Physical Properties

Molecular Formula C20H16ClN3O3
Molecular Weight 381.81