p-chlorophenylacetyl chloride structure
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Common Name | p-chlorophenylacetyl chloride | ||
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CAS Number | 25026-34-0 | Molecular Weight | 189.039 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 254.7±23.0 °C at 760 mmHg | |
Molecular Formula | C8H6Cl2O | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 103.0±22.9 °C | |
Symbol |
GHS05, GHS07 |
Signal Word | Danger |
Name | 2-(4-chlorophenyl)acetyl chloride |
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Synonym | More Synonyms |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 254.7±23.0 °C at 760 mmHg |
Molecular Formula | C8H6Cl2O |
Molecular Weight | 189.039 |
Flash Point | 103.0±22.9 °C |
Exact Mass | 187.979568 |
PSA | 17.07000 |
LogP | 2.83 |
Vapour Pressure | 0.0±0.5 mmHg at 25°C |
Index of Refraction | 1.552 |
Synonym:4-Chlorophenylacetyl chloride Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Causes burns.Corrosive. Potential Health Effects Eye: Causes eye burns. May cause chemical conjunctivitis and corneal damage. Skin: Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color. Ingestion: May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects. Inhalation: May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. May cause systemic effects. Chronic: Effects may be delayed. Section 4 - FIRST AID MEASURES Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes). Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes. Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Discard contaminated shoes. Storage: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 25026-34-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: red-pink Odor: None reported. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H6Cl2O Molecular Weight: 189.04 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, excess heat. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 25026-34-0 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Chlorobenzeneacetyl chloride, 98% - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3265 Packing Group: II IMO Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3265 Packing Group: II RID/ADR Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3265 Packing group: II Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 34 Causes burns. Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 25026-34-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 25026-34-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 25026-34-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
Symbol |
GHS05, GHS07 |
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Signal Word | Danger |
Hazard Statements | H302-H314-H317 |
Precautionary Statements | P280-P305 + P351 + P338-P310 |
Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | C:Corrosive; |
Risk Phrases | R34 |
Safety Phrases | S26-S36/37/39-S45-S24/25 |
RIDADR | UN 3265 8/PG 2 |
WGK Germany | 3 |
Packaging Group | II |
Hazard Class | 8 |
HS Code | 2916399090 |
~97% p-chlorophenyla... CAS#:25026-34-0 |
Literature: Chatterjee, Arnab K.; Liu, Hong; Tully, David C.; Guo, Jianhua; Epple, Robert; Russo, Ross; Williams, Jennifer; Roberts, Michael; Tuntland, Tove; Chang, Jonathan; Gordon, Perry; Hollenbeck, Thomas; Tumanut, Christine; Li, Jun; Harris, Jennifer L. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 10 p. 2899 - 2903 |
~% p-chlorophenyla... CAS#:25026-34-0 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 15 p. 1723 - 1727 |
~% p-chlorophenyla... CAS#:25026-34-0 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 15 p. 1723 - 1727 |
~% p-chlorophenyla... CAS#:25026-34-0 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 15 p. 1723 - 1727 |
~% p-chlorophenyla... CAS#:25026-34-0 |
Literature: US4724263 A1, ; |
~% p-chlorophenyla... CAS#:25026-34-0 |
Literature: Scientia Pharmaceutica, , vol. 69, # 4 p. 329 - 350 |
~% p-chlorophenyla... CAS#:25026-34-0 |
Literature: Scientia Pharmaceutica, , vol. 69, # 4 p. 329 - 350 |
~% p-chlorophenyla... CAS#:25026-34-0 |
Literature: Scientia Pharmaceutica, , vol. 69, # 4 p. 329 - 350 |
~% p-chlorophenyla... CAS#:25026-34-0 |
Literature: Biochemische Zeitschrift, , vol. 27, p. 102 |
Precursor 9 | |
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DownStream 10 | |
HS Code | 2916399090 |
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Summary | 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
4-chlorophenylacetic acid chloride |
parachlorophenyl acetyl chloride |
Benzeneacetyl chloride, 4-chloro- |
4-Chlorobenzeneacetyl chloride |
MFCD00037111 |
EINECS 246-571-1 |
p-chlorophenylacetyl chloride |
4-Chlorophenylacetyl chloride |
(4-Chlorophenyl)acetyl chloride |