Z-Asp-Glu-Val-Asp-chloromethylketone

Modify Date: 2024-01-14 21:30:24

Z-Asp-Glu-Val-Asp-chloromethylketone Structure
Z-Asp-Glu-Val-Asp-chloromethylketone structure
Common Name Z-Asp-Glu-Val-Asp-chloromethylketone
CAS Number 250584-13-5 Molecular Weight 643.04
Density N/A Boiling Point N/A
Molecular Formula C27H35ClN4O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Z-Asp-Glu-Val-Asp-chloromethylketone


Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro[1].

 Names

Name z-devd-cmk
Synonym More Synonyms

 Z-Asp-Glu-Val-Asp-chloromethylketone Biological Activity

Description Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro[1].
Related Catalog
Target

Papain, Cathepsins B, Cathepsins L, Cathepsins V, Cathepsins S, Cathepsins X[1]

References

[1]. Rozman-Pungercar J, et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 2003 Aug;10(8):881-8.  

 Chemical & Physical Properties

Molecular Formula C27H35ClN4O12
Molecular Weight 643.04
Exact Mass 642.19400
PSA 254.60000
LogP 1.57750
Storage condition -15°C

 Synonyms

Z-ASP-GLU-VAL-ASP-CMK
Z-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE
Z-Asp-Glu-Val-Asp-chloromethyketone