Methyldopate hydrochloride

Modify Date: 2024-01-02 15:02:35

Methyldopate hydrochloride Structure
Methyldopate hydrochloride structure
Common Name Methyldopate hydrochloride
CAS Number 2508-79-4 Molecular Weight 275.72900
Density 1.243g/cm3 Boiling Point 398ºC at 760 mmHg
Molecular Formula C12H18ClNO4 Melting Point N/A
MSDS N/A Flash Point 194.5ºC

 Use of Methyldopate hydrochloride


Methyldopate hydrochloride is an ethyl ester hydrochloride prodrug of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate hydrochloride has the potential for severe hypertension research[1].

 Names

Name ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate,hydrochloride
Synonym More Synonyms

 Methyldopate hydrochloride Biological Activity

Description Methyldopate hydrochloride is an ethyl ester hydrochloride prodrug of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate hydrochloride has the potential for severe hypertension research[1].
Related Catalog
References

[1]. P D Walson, et al. Metabolic disposition and cardiovascular effects of methyldopate in unanesthetized rhesus monkeys. J Pharmacol Exp Ther. 1975 Oct;195(1):151-8.

 Chemical & Physical Properties

Density 1.243g/cm3
Boiling Point 398ºC at 760 mmHg
Molecular Formula C12H18ClNO4
Molecular Weight 275.72900
Flash Point 194.5ºC
Exact Mass 275.09200
PSA 92.78000
LogP 2.42310
Vapour Pressure 6.62E-07mmHg at 25°C
Index of Refraction 1.572

 Synonyms

METHYLDOPATE HYDROCHLORIDE
Methyldopa ethyl hydrochloride
EINECS 219-720-3
Methyldopa ethyl ester hydrochloride
UNII-7PX435DN5A
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