(2E,4E)-Deca-2,4-dienal

Modify Date: 2024-01-09 23:39:28

(2E,4E)-Deca-2,4-dienal Structure
(2E,4E)-Deca-2,4-dienal structure
Common Name (2E,4E)-Deca-2,4-dienal
CAS Number 25152-84-5 Molecular Weight 152.233
Density 0.9±0.1 g/cm3 Boiling Point 244.6±0.0 °C at 760 mmHg
Molecular Formula C10H16O Melting Point N/A
MSDS Chinese USA Flash Point 102.3±11.0 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of (2E,4E)-Deca-2,4-dienal


trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid[1].

 Names

Name trans,trans-2,4-Decadien-1-al
Synonym More Synonyms

 (2E,4E)-Deca-2,4-dienal Biological Activity

Description trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid[1].
Related Catalog
In Vitro Two metabolic pathways for the biotransformation of trans,trans-2,4-Decadienal (tt-DDE) in vivo are proposed: (i) the oxidation of tt-DDE to the corresponding carboxylic acid, 2,4-decadienoic acid, in liver cells and (ii) glutathione (GHS) conjugation, GSH breakdown, and aldehyde reduction, which generate cysteine-conjugated 2,4-decadien-1-ol in both liver and lung cells.
References

[1]. Kao-Lu Pan, et al. Identification of trans,trans-2,4-decadienal metabolites in mouse and human cells using liquid chromatography-mass spectrometry. Chem Res Toxicol. 2014 Oct 20;27(10):1707-19.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 244.6±0.0 °C at 760 mmHg
Molecular Formula C10H16O
Molecular Weight 152.233
Flash Point 102.3±11.0 °C
Exact Mass 152.120117
PSA 17.07000
LogP 3.18
Vapour density >1 (vs air)
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.459
Storage condition Refrigerator (+4°C)
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HD3000000
CHEMICAL NAME :
2,4-Decadienal, (E,E)-
CAS REGISTRY NUMBER :
25152-84-5
BEILSTEIN REFERENCE NO. :
1704897
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H16-O
MOLECULAR WEIGHT :
152.26

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS HD3000000
Packaging Group III

 Synthetic Route

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trans,trans-2,4-decadienal induces mitochondrial dysfunction and oxidative stress.

J. Bioenerg. Biomembr. 40(2) , 103-9, (2008)

Lipid peroxidation produces a large number of reactive aldehydes as secondary products. We have previously shown that the reaction of cytochrome c with trans,trans-2,4-decadienal (DDE), an aldehyde ge...

 Synonyms

DDA
FEMA 3135
DECADIENEALDEHYDE
(2E,4E)-2,4-Decadienal
2,4-Decadienal, (2E,4E)-
2E,4E-DECADIENAL
2,4-Decadienal
(2E,4E)-Deca-2,4-dienal
trans,trans-2,4-Decadienal
2,4-DECADIEN-1-AL
trans-2,4-Decadienal
trans,trans-deca-2,4-dienal
2-trans,4-trans-n-decadienal
Decadienal
2,4-trans,trans-decadienal
2-trans,4-trans decadienal
EINECS 246-668-9
T2 T4 DECADIENAL
2.4-Decadienal
MFCD00007007
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