N-ISOBUTYL-2,6,8-DECATRIENAMIDE

Modify Date: 2024-01-02 18:21:37

N-ISOBUTYL-2,6,8-DECATRIENAMIDE Structure
N-ISOBUTYL-2,6,8-DECATRIENAMIDE structure
Common Name N-ISOBUTYL-2,6,8-DECATRIENAMIDE
CAS Number 25394-57-4 Molecular Weight 221.34
Density N/A Boiling Point N/A
Molecular Formula C14H23NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-ISOBUTYL-2,6,8-DECATRIENAMIDE


Spilanthol is an orally active analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial and insecticidal compound.pilanthol can induce cAMP to inhibit negative regulation of urinary concentration mechanism. Spilanthol can be use as diuretic research[1][4][5].

 Names

Name spilanthol

 N-ISOBUTYL-2,6,8-DECATRIENAMIDE Biological Activity

Description Spilanthol is an orally active analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial and insecticidal compound.pilanthol can induce cAMP to inhibit negative regulation of urinary concentration mechanism. Spilanthol can be use as diuretic research[1][4][5].
Related Catalog
Target

Cyclic Adenosine monophosphate (cAMP)[5]

References

[1]. Alan F, et al. Spilanthol: occurrence, extraction, chemistry and biological activities. Elsevier. 2016:128-133

[2]. Déciga-Campos M, et al. Antinociceptive effect of Heliopsis longipes extract and affinin in mice. Planta Med. 2010 May;76(7):665-70.  

[3]. Huang WC, et al. Spilanthol Inhibits COX-2 and ICAM-1 Expression via Suppression of NF-κB and MAPK Signaling in Interleukin-1β-Stimulated Human Lung Epithelial Cells. Inflammation. 2018 Oct;41(5):1934-1944.  

[4]. de Freitas-Blanco VS, et al. Spilanthol, the Principal Alkylamide from Acmella oleracea, Attenuates 5-Fluorouracil-Induced Intestinal Mucositis in Mice. Planta Med. 2019 Feb;85(3):203-209.  

[5]. [5]Gerbino A, et al.. Spilanthol from Acmella Oleracea Lowers the Intracellular Levels of cAMP Impairing NKCC2 Phosphorylation and Water Channel AQP2 Membrane Expression in Mouse Kidney. PLoS One. 2016 May 23;11(5):e0156021.  

 Chemical & Physical Properties

Molecular Formula C14H23NO
Molecular Weight 221.34
Exact Mass 221.17800
PSA 29.10000
LogP 3.61820
Vapour Pressure 4.02E-06mmHg at 25°C