Phellopterin

Modify Date: 2024-01-03 11:32:51

Phellopterin Structure
Phellopterin structure
Common Name Phellopterin
CAS Number 2543-94-4 Molecular Weight 300.306
Density 1.2±0.1 g/cm3 Boiling Point 480.4±45.0 °C at 760 mmHg
Molecular Formula C17H16O5 Melting Point 102-103ºC
MSDS N/A Flash Point 244.4±28.7 °C

 Use of Phellopterin


Phellopterin is a natural product isolated from P. trifoliata. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].

 Names

Name 4-methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
Synonym More Synonyms

 Phellopterin Biological Activity

Description Phellopterin is a natural product isolated from P. trifoliata. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].
Related Catalog
References

[1]. Nizamutdinova IT, et al. Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. Int Immunopharmacol. 2008 May;8(5):670-8.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 480.4±45.0 °C at 760 mmHg
Melting Point 102-103ºC
Molecular Formula C17H16O5
Molecular Weight 300.306
Flash Point 244.4±28.7 °C
Exact Mass 300.099762
PSA 61.81000
LogP 4.19
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.592

 Safety Information

Hazard Codes Xi
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Phellopterin
4-Methoxy-9-[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one
4-Methoxy-9-[(3-methylbut-2-en-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one
7H-Furo[3,2-g][1]benzopyran-7-one, 4-methoxy-9-[(3-methyl-2-buten-1-yl)oxy]-
7H-Furo(3,2-g)(1)benzopyran-7-one, 4-methoxy-9-((3-methyl-2-butenyl)oxy)-
4-Methoxy-9-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g]chromen-7-one
fellopterin
Phelloterin
5-methoxy-8-prenyloxypsoralen
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