Adenylyl Imidodiphosphate

Modify Date: 2024-01-10 10:34:43

Adenylyl Imidodiphosphate structure	Common Name	Adenylyl Imidodiphosphate
	CAS Number	25612-73-1	Molecular Weight	506.19600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₇N₆O₁₂P₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Adenylyl Imidodiphosphate

AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolysable ATP analogue[1].

Name	amp-pnp
Synonym	More Synonyms

Description	AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolysable ATP analogue[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	AMP-PNP binding induces an inward rotation and shift of the transmembrane helices of LptFG and LptC to tighten the cavity, with the closure of two lateral gates, to eventually expel LPS into the bridge[1]. AMP-PNP significantly inhibits the ATPase activity of sfLptB2FGC, which was used to mimic and lock an ATP-bound state of sfLptB2FGC[1].
References	[1]. Tang X, et al. Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism. Nat Commun. 2019 Sep 13;10(1):4175.

Molecular Formula	C₁₀H₁₇N₆O₁₂P₃
Molecular Weight	506.19600
Exact Mass	506.01200
PSA	311.36000

Adenylyl Imidodiphosphate MSDS(Chinese)

Adenosine beta,gamma-imidotriphosphate

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