N-Methyl-DL-valine

Modify Date: 2024-01-11 19:33:16

N-Methyl-DL-valine Structure
N-Methyl-DL-valine structure
Common Name N-Methyl-DL-valine
CAS Number 2566-32-7 Molecular Weight 167.634
Density 0.995 Boiling Point N/A
Molecular Formula C6H14ClNO2 Melting Point 82-84ºC
MSDS USA Flash Point N/A

 Use of N-Methyl-DL-valine


N-Methyl-DL-valine is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability[1][2].

 Names

Name N-methylvaline
Synonym More Synonyms

 N-Methyl-DL-valine Biological Activity

Description N-Methyl-DL-valine is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability[1][2].
Related Catalog
References

[1]. M. Pasteels, et al. Uptake and metabolism of [14C]rinderine and [14C]retronecine in leaf-beetles of the genus Platyphora and alkaloid accumulation in the exocrine defensive secretions. Chemoecology. 2003;13:55–62.

[2]. Philip N Moquist, et al. Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux–positive Tumor Models. Mol Cancer Ther.2021;20(2): 320–328.

 Chemical & Physical Properties

Density 0.995
Melting Point 82-84ºC
Molecular Formula C6H14ClNO2
Molecular Weight 167.634
Exact Mass 167.071304
PSA 49.33000
LogP 1.50790
Storage condition Store at RT.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922499990

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles1

More Articles
Investigation of 60Co γ-irradiated l-(−) malic acid, N-methyl-dl-valine and l-glutamic acid γ-ethyl ester by electron paramagnetic resonance technique Baskin, M.H., Aydin, M., and Osmanoğlu, S.

J. Mol. Struct. 983 , 200-202, (2010)

 Synonyms

methyl-valine
N-Methylvaline hydrochloride
N-METHYL-DL-VALINE HYDROCHLORIDE
Valine, N-methyl-, hydrochloride (1:1)
H-(S,R)-NMeVal-OH
N-ME-DL-VAL-OH HCL
N-Methyl-dl-valine,HCl
N-methyl-valine
N-Methylvaline hydrochloride (1:1)