MIPS-21335

Modify Date: 2024-01-08 07:36:45

MIPS-21335 structure	Common Name	MIPS-21335
	CAS Number	2569296-51-9	Molecular Weight	487.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₁N₇O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MIPS-21335

MIPS-21335 is an PI3KC2α inhibitor (IC50: 7 nM). MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ (IC50: 0.043, 0.140, 0.386, 0.742 μM). MIPS-21335 has antithrombotic effect[1].

Name	MIPS-21335

Description	MIPS-21335 is an PI3KC2α inhibitor (IC50: 7 nM). MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ (IC50: 0.043, 0.140, 0.386, 0.742 μM). MIPS-21335 has antithrombotic effect[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> PI3K/Akt/mTOR >> PI4K
Target	7 nM (PI3KC2α)[1].
References	[1]. Selvadurai MV, et al. Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation. Sci Transl Med. 2020 Jul 22;12(553):eaar8430.

Molecular Formula	C₂₄H₂₁N₇O₅
Molecular Weight	487.47