Posovolone
Modify Date: 2024-01-23 08:09:33
Posovolone structure
|
Common Name | Posovolone | ||
|---|---|---|---|---|
| CAS Number | 256955-84-7 | Molecular Weight | 428.60700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H40N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PosovolonePosovolone (Co 134444) is an orally active sedative-hypnotic neuroactive steroid. Posovolone has anticonvulsant and anxiolytic-like activity as well as ataxic effects[1]. |
| Name | 1-[(3S,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3-(methoxymethyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-imidazol-1-ylethanone |
|---|---|
| Synonym | More Synonyms |
| Description | Posovolone (Co 134444) is an orally active sedative-hypnotic neuroactive steroid. Posovolone has anticonvulsant and anxiolytic-like activity as well as ataxic effects[1]. |
|---|---|
| Related Catalog | |
| In Vitro | In mice, Co 134444 (0.5-10 mg/kg, IP, 15 min; 1-60 mg/kg, PO; 30 min) demonstrates efficacy against pentylenetetrazol (PTZ)-induced seizures with an ED50 of 3.3 mg/kg after IP administration and 9.8 mg/kg orally. Similarly, protection against maximal electroshock (MES) is observed with an ED50 of 4.8 mg/kg IP and 20.6 mg/kg PO. In rats, Co134444 (10-40 mg/kg; PO; 30 min) protects against PTZ-induced seizures and MES-induced seizures with an ED50 of 23.6 mg/kg and 25.3 mg/kg, respectively[1]. |
| References |
| Molecular Formula | C26H40N2O3 |
|---|---|
| Molecular Weight | 428.60700 |
| Exact Mass | 428.30400 |
| PSA | 64.35000 |
| LogP | 4.48860 |
| UNII-1GA9JVO9ZA |
| Pregnan-20-one,3-hydroxy-21-(1H-imidazol-1-yl)-3-(methoxymethyl)-,(3alpha,5alpha) |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Posovolone
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Posovolone
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
Get all suppliers and price by the below link:
Price: ￥5000/5 mg
Reference only. check more Posovolone price