FP-Biotin

Modify Date: 2024-01-13 11:08:32

FP-Biotin structure	Common Name	FP-Biotin
	CAS Number	259270-28-5	Molecular Weight	592.75
	Density	1.125g/cm3	Boiling Point	851.3ºC at 760 mmHg
	Molecular Formula	C₂₇H₅₀FN₄O₅PS	Melting Point	N/A
	MSDS	N/A	Flash Point	468.6ºC

Use of FP-Biotin

FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads[1][2][3].

Name	10-[ethoxy(fluoro)phosphoryl]-N-[5-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoylamino]pentyl]decanamide
Synonym	More Synonyms

Description	FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	FP-biotin has good reactivity with human AChE and BChE despite its large biotin group. FP-biotin is suitable for the proposed task of identifying organophosphorus toxicants reactive proteins[1].
References	[1]. Schopfer LM, et al. Reaction kinetics of biotinylated organophosphorus toxicant, FP-biotin, with human acetylcholinesterase and human butyrylcholinesterase. Chem Res Toxicol. 2005;18(4):747-754. [2]. Baggelaar MP, et al. Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases. ACS Chem Biol. 2017;12(3):852-861. [3]. Grigoryan H, et al. Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine. Chem Biol Interact. 2009;180(3):492-498.

Density	1.125g/cm3
Boiling Point	851.3ºC at 760 mmHg
Molecular Formula	C₂₇H₅₀FN₄O₅PS
Molecular Weight	592.75
Flash Point	468.6ºC
Exact Mass	592.32200
PSA	171.21000
LogP	7.08420
Vapour Pressure	2.82E-29mmHg at 25°C
Index of Refraction	1.497

FP-biotin

DC Chemicals Limited
China
Product Name: FP-Biotin
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: FP-Biotin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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