PD-1/PD-L1-IN-18

Modify Date: 2024-01-10 04:45:26

PD-1/PD-L1-IN-18 structure	Common Name	PD-1/PD-L1-IN-18
	CAS Number	2648851-27-6	Molecular Weight	685.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₃₂BrCl₂N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PD-1/PD-L1-IN-18

PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity[1].

Name	PD-1/PD-L1-IN-18

Description	PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
References	[1]. Liu Liu, et al. Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[ c][1,2,5]oxadiazole Derivatives as Potent PD-L1 Inhibitors with In Vivo Antitumor Activity. J Med Chem. 2021 Jun 24;64(12):8391-8409.

Molecular Formula	C₃₃H₃₂BrCl₂N₃O₄
Molecular Weight	685.43