Medrysone

Modify Date: 2024-01-04 12:00:35

Medrysone Structure
Medrysone structure
Common Name Medrysone
CAS Number 2668-66-8 Molecular Weight 344.48800
Density 1.13g/cm3 Boiling Point 492.3ºC at 760mmHg
Molecular Formula C22H32O3 Melting Point N/A
MSDS Chinese USA Flash Point 265.7ºC

 Use of Medrysone


Medrysone is a corticosteroid, in ophthalmology for the treatment of eye inflammations.

 Names

Name 6α-Methyl-11β-hydroxyprogesterone
Synonym More Synonyms

 Medrysone Biological Activity

Description Medrysone is a corticosteroid, in ophthalmology for the treatment of eye inflammations.
Related Catalog

 Chemical & Physical Properties

Density 1.13g/cm3
Boiling Point 492.3ºC at 760mmHg
Molecular Formula C22H32O3
Molecular Weight 344.48800
Flash Point 265.7ºC
Exact Mass 344.23500
PSA 54.37000
LogP 3.94030
Vapour Pressure 9.3E-12mmHg at 25°C
Index of Refraction 1.552
Storage condition 2-8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5250000
CHEMICAL NAME :
Pregn-4-ene-3,20-dione, 11-beta-hydroxy-6-alpha-methyl-
CAS REGISTRY NUMBER :
2668-66-8
LAST UPDATED :
199504
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H32-O3
MOLECULAR WEIGHT :
344.54
WISWESSER LINE NOTATION :
L E5 B666 OV MUTJ A1 CQ E1 FV1 L1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
338 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3713 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 711 (estimated) No. of Female Employees: 328 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS TU5250000

 Synthetic Route

~%

Medrysone Structure

Medrysone

CAS#:2668-66-8

Literature: Upjohn Co. Patent: US2864837 , 1958 ;

~%

Medrysone Structure

Medrysone

CAS#:2668-66-8

Literature: Upjohn Co. Patent: US2864837 , 1958 ;

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles11

More Articles
Ocular pemphigus.

J. Egypt. Med. Assoc. 61(7-8) , 511-22, (1978)

Efficacy of medrysone as anti-inflammatory agent.

Indian J. Ophthalmol. 33(5) , 295-7, (1985)

Management of vernal conjunctivitis with steroid induced glaucoma--a comparative study.

Indian J. Ophthalmol. 35(5-6) , 298-301, (1987)

 Synonyms

medrysone