URAT1&XO inhibitor 1

Modify Date: 2024-01-02 12:04:52

URAT1&XO inhibitor 1 structure	Common Name	URAT1&XO inhibitor 1
	CAS Number	2669726-78-5	Molecular Weight	403.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₃N₅O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of URAT1&XO inhibitor 1

URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research[1].

Name	URAT1&XO inhibitor 1

Description	URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> URAT1 Research Areas >> Metabolic Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase
References	[1]. Fengwei Lin, et al. Identification of 5-[5-cyano-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamido] thiazole-4-carboxylic acid as a promising dual inhibitor of urate transporter 1 and xanthine oxidase. European Journal of Medicinal Chemistry. Volume 257, 5 September 2023, 115532.

Molecular Formula	C₂₀H₁₃N₅O₃S
Molecular Weight	403.41

URAT1&XO inhibitor 1

Use of URAT1&XO inhibitor 1

Names

URAT1&XO inhibitor 1 Biological Activity

Chemical & Physical Properties