TMDJ-035

Modify Date: 2024-01-13 04:35:36

TMDJ-035 Structure
TMDJ-035 structure
Common Name TMDJ-035
CAS Number 2681302-83-8 Molecular Weight 347.29
Density N/A Boiling Point N/A
Molecular Formula C16H12F3N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TMDJ-035


TMDJ-035 is a selective RyR2 inhibitor. TMDJ-035 suppresses abnormal Ca2+ waves and transients in isolated cardiomyocytes from RyR2-mutated mice. TMDJ-035is a tool for studying the mechanism and dynamics of RyR2 channel gating[1].

 Names

Name TMDJ-035

 TMDJ-035 Biological Activity

Description TMDJ-035 is a selective RyR2 inhibitor. TMDJ-035 suppresses abnormal Ca2+ waves and transients in isolated cardiomyocytes from RyR2-mutated mice. TMDJ-035is a tool for studying the mechanism and dynamics of RyR2 channel gating[1].
Related Catalog
References

[1]. Ryosuke Ishida, et al. A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment. European Journal of Medicinal Chemistry

 Chemical & Physical Properties

Molecular Formula C16H12F3N5O
Molecular Weight 347.29